Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited)

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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
CASH FLOWS FROM OPERATING ACTIVITIES:          
Net loss $ (15,135,485) $ (15,202,715) $ (47,705,458) $ (30,776,173)  
Adjustments to reconcile net loss to net cash used in operating activities:          
Depreciation and amortization 847,057 836,071 2,522,496 1,231,265  
Loss on disposal of fixed assets     13,200 4,155  
Stock-based compensation 577,581 505,730 1,627,756 1,052,970  
Amortization of debt discount     808,671 555,568  
Amortization of license revenue     (107,125) (107,125)  
Changes in operating assets and liabilities, net of acquisition:          
Accounts receivable     (246,640) (481,782)  
Inventories     (1,249,253) (201,472)  
Prepaid expenses and other current assets     (80,295) (969,042)  
Other assets     (20,116) (723,530)  
Accounts payable     (653,190) 5,228,096  
Accrued expenses     1,013,003 1,277,700  
Other current and non-current liabilities     191,393 (3,775)  
Net cash used in operating activities     (43,885,558) (23,913,145)  
CASH FLOWS FROM INVESTING ACTIVITIES:          
Sales of short-term investments     0 5,390,184  
Purchase of property and equipment     (1,276,594) (666,457)  
Cash acquired in acquisition transaction     0 12,500,000  
Net cash provided by (used in) investing activities     (1,276,594) 17,223,727  
CASH FLOWS FROM FINANCING ACTIVITIES:          
Principal payments on note payable     0 (4,444,444)  
Proceeds from issuance of common stock, net of offering expenses     42,944,831 0  
Proceeds from the exercise of stock options     6,328 7,504  
Proceeds from issuance of related party note payable     0 15,000,000 $ 15,000,000
Payment of debt issuance costs     0 (174,839)  
Payments on capital lease obligations     (9,395) 0  
Payments of leasehold improvement loan     (19,697) (12,279)  
Net cash provided by financing activities     42,922,067 10,375,942  
Net increase in cash and cash equivalents     (2,240,085) 3,686,524  
Cash and cash equivalents, including restricted cash - beginning of period     48,607,574 9,914,867 9,914,867
Cash and cash equivalents, including restricted cash - end of period $ 46,367,489 $ 13,601,391 $ 46,367,489 $ 13,601,391 $ 48,607,574