Annual report pursuant to Section 13 and 15(d)

8. STOCKHOLDERS' EQUITY (Details 1)

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8. STOCKHOLDERS' EQUITY (Details 1) - $ / shares
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Shares    
Outstanding at beginning of period 3,276,043 1,535,187
Forfeited (60,854) (94,024)
Expired (34,489) (47,476)
Granted 1,167,044 1,976,295
Exercised (5,513) (93,939)
Outstanding at end of period and expected to vest 4,342,231 3,276,043
Options exercisable 2,192,663  
Weighted Average Exercise Price    
Outstanding at beginning of period $ 5.52 $ 7.90
Forfeited 4.09 7.72
Expired 8.38 9.02
Granted 4.15 3.73
Exercised 3.31 2.68
Outstanding at end of period and expected to vest 5.16 $ 5.52
Options exercisable $ 6.30