Annual report pursuant to Section 13 and 15(d)

11. INCOME TAXES (Details 1)

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11. INCOME TAXES (Details 1) - USD ($)
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]    
Federal and state net operating loss carryforwards $ 26,080,351 $ 29,137,918
Federal and state research credits 525,248 4,526,201
Interest expense limitations carryforwards 1,159,422 0
Transaction costs 1,147,581 1,269,443
Deferred revenue 624,610 679,068
Accrued expenses and other 6,011,057 951,219
Total gross deferred tax assets 35,548,269 36,563,849
Less: valuation allowance for deferred tax assets (35,548,269) (36,563,849)
Net deferred tax assets $ 0 $ 0