Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited)

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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (13,067,955) $ (17,822,142)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 805,330 829,541
Loss on disposal of fixed assets 391 0
Stock-based compensation 637,263 514,784
Gain on transfer of plasma assets (11,527,421) 0
Amortization of debt discount 244,767 255,847
Loss on extinguishment of debt 9,962,495 0
Amortization of license revenue (35,708) (35,708)
Changes in operating assets and liabilities, net of acquisition:    
Accounts receivable 82,037 222,552
Inventories (25,310) 189,379
Prepaid expenses and other current assets (289,134) (652,474)
Deposits and other assets 179,644 (29,515)
Accounts payable (420,601) (202,754)
Accrued expenses (762,541) 88,640
Other current and non-current liabilities (70,442) 207,736
Net cash used in operating activities (14,287,184) (16,434,114)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchase of property and equipment (110,453) (549,246)
Net cash provided by (used in) investing activities (110,453) (549,246)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Principal payments on note payable (30,000,000) 0
Payment of end of term fee (2,760,000) 0
Payment of debt refinancing fees (6,499,867) 0
Proceeds from issuance of note payable 45,000,000 0
Payment of debt issuance costs (1,555,762) 0
Payments on capital lease obligations (7,308) 0
Payments of leasehold improvement loan 0 (4,377)
Net cash provided by (used in) financing activities 4,177,063 (4,377)
Net (decrease) increase in cash and cash equivalents (10,220,574) (16,987,737)
Cash and cash equivalents, including restricted cash - beginning of period 26,754,852 48,607,574
Cash and cash equivalents, including restricted cash - end of period $ 16,534,278 $ 31,619,837