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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (26,279,827) $ (32,569,973)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,611,422 1,675,439
Loss on disposal of property and equipment 8,788 2,459
Stock-based compensation 1,363,999 1,050,175
Gain on transfer of plasma assets (11,527,421) 0
Amortization of debt discount 340,481 525,135
Loss on extinguishment of debt 9,962,495 0
Amortization of license revenue (71,417) (71,417)
Changes in operating assets and liabilities:    
Accounts receivable (3,694,222) 82,960
Inventories (5,175,148) 381,213
Prepaid expenses and other current assets 163,747 (380,626)
Deposits and other assets 118,832 (23,365)
Accounts payable 887,753 (2,819,792)
Accrued expenses (529,589) 554,885
Other current and non-current liabilities (91,029) 250,754
Net cash used in operating activities (32,911,136) (31,342,153)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchase of property and equipment (245,675) (1,046,375)
Net cash provided by (used in) investing activities (245,675) (1,046,375)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Principal payments on note payable (30,000,000) 0
Payment of end of term fee (2,760,000) 0
Payment of debt refinancing fees (6,499,867) 0
Proceeds from issuance of common stock, net of offering expenses 48,397,088 42,946,111
Proceeds from the exercise of stock options 75,048 0
Proceeds from issuance of note payable 72,500,000 0
Payment of debt issuance costs (1,679,661) 0
Payments on finance lease obligations (14,740) (2,329)
Payments of leasehold improvement loan 0 (8,853)
Net cash provided by financing activities 80,017,868 42,934,929
Net (decrease) increase in cash and cash equivalents 46,861,057 10,546,401
Cash and cash equivalents, including restricted cash - beginning of period 26,754,852 48,607,574
Cash and cash equivalents, including restricted cash - end of period $ 73,615,909 $ 59,153,975

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